In the ever-expanding world of functional foods, few ingredients spark as much hype—and debate—as Chaga mushroom. Often promoted as “nature’s most powerful antioxidant” and celebrated for boasting one of the highest ORAC values ever measured, this rugged, charcoal-like fungus has earned a reputation as a superfood with almost mythical benefits.
But how much of the buzz is backed by science, and how much is clever marketing? Is Chaga truly the antioxidant heavyweight it’s claimed to be, or is the reality more complex?
At Vital Pour, our goal is to separate fact from fiction—giving you clear, evidence-based insights so you can decide whether Chaga deserves a place in your wellness routine.
Having personally incorporated Chaga into my wellness routine for over two years, I can attest to its subtle yet profound effects. Unlike the immediate energy boost you might get from caffeine, Chaga offers something different—a sustained sense of vitality and resilience that builds over time. It's become an essential part of my morning mushroom coffee ritual, providing not just antioxidant support but a deeper connection to nature's wisdom.
This comprehensive guide will take you on a journey through the fascinating world of Chaga mushroom. We'll explore its remarkable history, dive deep into the science behind its antioxidant properties, and separate fact from fiction when it comes to those impressive ORAC claims. Whether you're a seasoned biohacker or someone just beginning to explore functional mushrooms, you'll discover everything you need to know about this remarkable fungus.
Here's what we'll cover:
- The fascinating biology and history of Chaga mushroom
- The truth about ORAC values and antioxidant measurements
- Science-backed health benefits beyond antioxidant activity
- How Chaga compares to other antioxidant-rich foods
- Practical guidance on choosing and using Chaga supplements
- Safety considerations and potential interactions
Let's embark on this exploration of one of nature's most intriguing and potentially powerful wellness allies.
What is Chaga Mushroom? Understanding Nature's Black Gold
Chaga mushroom, scientifically known as Inonotus obliquus, is unlike any other fungus you've encountered. This parasitic fungus doesn't look like the typical mushrooms you'd find in a grocery store. Instead, it appears as a black, crusty mass that resembles burnt charcoal clinging to the trunks of birch trees throughout the northern hemisphere.
This distinctive appearance has earned Chaga several colorful nicknames throughout history, including "black mass," "clinker polypore," "sterile conk," and perhaps most poetically, "the king of medicinal mushrooms." But don't let its uninviting exterior fool you—beneath that charcoal-like surface lies a treasure trove of bioactive compounds that have been revered for centuries.
The Unique Biology of Chaga
What makes Chaga truly special is its parasitic relationship with birch trees (Betula species). Unlike other mushrooms that grow from the ground or decompose dead wood, Chaga forms a symbiotic relationship with living birch trees, slowly extracting nutrients and compounds from its host over decades [1].
This extended relationship—which can last 30 to 80 years—allows Chaga to accumulate an extraordinary concentration of bioactive compounds. Some of these compounds, like betulinic acid, actually originate from the birch tree itself, making Chaga a unique fusion of fungal and plant chemistry [2].
The slow growth process is crucial to Chaga's potency. In the harsh climates of northern regions where temperatures can plummet well below freezing, Chaga develops its remarkable antioxidant compounds as a survival mechanism. These compounds protect both the fungus and its host tree from oxidative stress caused by extreme weather conditions, UV radiation, and environmental pollutants.
A Rich History in Traditional Medicine
Long before modern science began investigating Chaga's properties, indigenous peoples of Siberia, Russia, and northern regions of North America had been using this remarkable fungus for medicinal purposes. Historical records show that Chaga has been employed in folk medicine since the 16th century [3].
In traditional Siberian medicine, Chaga was prepared as a tea or tincture and used to treat a wide range of ailments, including:
- Gastrointestinal disorders and stomach ulcers
- Cardiovascular diseases
- Diabetes and blood sugar regulation
- Liver diseases and detoxification
- Tuberculosis and respiratory infections
- Various forms of cancer
Russian folk healers particularly prized Chaga for its ability to boost overall vitality and longevity. They observed that regular consumption seemed to enhance resistance to disease and promote a general sense of well-being—observations that modern science is now beginning to validate.
The Antioxidant Controversy: Separating Fact from Fiction
When it comes to Chaga's antioxidant properties, there's a lot of conflicting information circulating online. You've probably seen claims that Chaga has "the highest ORAC value ever recorded" or that it's "52 times more antioxidant-rich than blueberries." But what's the truth behind these bold statements?
Understanding ORAC: What It Measures and What It Doesn't
ORAC (Oxygen Radical Absorbance Capacity) is a laboratory test developed in the 1980s to measure how well a substance can neutralize free radicals in a controlled environment [4]. The test became popular as a way to rank foods by their antioxidant potential, with higher ORAC scores supposedly indicating better antioxidant benefits.
However, there's a crucial limitation that many marketers conveniently ignore: ORAC values measured in a test tube don't necessarily translate to antioxidant benefits in your body. This is why the USDA actually withdrew its ORAC database in 2012, stating that ORAC values alone shouldn't be used to determine health benefits [5].
The Reality of Chaga's ORAC Claims
Here's where things get interesting—and a bit controversial. While numerous websites claim that Chaga has ORAC values ranging from 146,700 to over 230,000 per 100 grams, there's surprisingly little peer-reviewed scientific evidence to support these specific numbers.
A thorough investigation by mushroom experts at FreshCap Mushrooms found that many of these claims trace back to unverified sources, with some pointing to research that may not have actually been conducted [6]. The often-cited "Tufts University study" that supposedly confirmed Chaga's supreme ORAC status appears to be more marketing myth than scientific fact.
What the Science Actually Shows
Despite the questionable ORAC claims, legitimate scientific research has demonstrated that Chaga does possess significant antioxidant properties. A 2005 study published in the Journal of Agricultural and Food Chemistry compared Chaga to four other medicinal mushrooms and found that it outperformed them all in antioxidant tests [7].
More importantly, researchers have identified the specific compounds responsible for Chaga's antioxidant activity:
Polyphenols: These plant compounds appear to offer the strongest protection against oxidative stress in Chaga extracts [8].
Melanin: The dark pigment that gives Chaga its black exterior also contributes significantly to its antioxidant capacity [9].
Polysaccharides: Complex carbohydrates found in Chaga that demonstrate both antioxidant and immune-supporting properties [10].
Triterpenoids: Including betulinic acid derived from birch trees, these compounds offer multiple health benefits beyond antioxidant activity [11].
Beyond ORAC: How Chaga Really Works
What makes Chaga truly special isn't necessarily its ORAC score, but rather its ability to work through multiple pathways in your body. Research suggests that Chaga may:
- Stimulate your body's natural antioxidant systems: Rather than just providing antioxidants, Chaga may help boost your body's production of powerful enzymes like superoxide dismutase (SOD) and glutathione [12].
- Provide sustained antioxidant activity: Unlike single antioxidant compounds that are quickly metabolized, Chaga's complex mixture of bioactive compounds may provide longer-lasting protection.
- Support cellular repair mechanisms: Some studies suggest that Chaga compounds can help repair existing free radical damage, not just prevent new damage [13].
The bottom line? While Chaga's exact ORAC value may be debated, there's solid scientific evidence that it possesses potent antioxidant properties that can benefit your health in meaningful ways.
Beyond Antioxidants: The Comprehensive Health Benefits of Chaga
While Chaga's antioxidant properties often steal the spotlight, this remarkable mushroom offers a much broader spectrum of health benefits. Modern research has validated many of the traditional uses of Chaga, revealing a complex profile of bioactive compounds that work synergistically to support multiple aspects of health.
Immune System Support and Modulation
One of Chaga's most well-documented benefits is its ability to support and modulate immune function. Unlike simple immune "boosters" that just ramp up immune activity, Chaga appears to help balance immune responses—strengthening them when needed while preventing overactivity that can lead to inflammation [14].
A 2005 study published in BMC Complementary and Alternative Medicine found that Chaga extracts significantly enhanced immune cell activity in laboratory tests [15]. The polysaccharides in Chaga, particularly beta-glucans, appear to be key players in this immune-supporting activity.
In my own experience, I've noticed that since incorporating Chaga into my routine, I seem to bounce back more quickly from minor illnesses and feel more resilient during stressful periods. While this is anecdotal, it aligns with what traditional users have reported for centuries.
Anti-Inflammatory Properties
Chronic inflammation is increasingly recognized as a root cause of many modern health issues, from cardiovascular disease to cognitive decline. Chaga's anti-inflammatory properties may help address this underlying problem at the cellular level.
Research has shown that Chaga extracts can significantly reduce the production of inflammatory markers, including cytokines and nitric oxide [16]. A 2020 study found that specific compounds in Chaga could inhibit inflammatory pathways while promoting the production of anti-inflammatory substances [17].
Potential Cancer-Fighting Properties
Perhaps one of the most exciting areas of Chaga research involves its potential anti-cancer properties. While it's important to note that Chaga is not a cancer treatment, laboratory studies have shown promising results that warrant further investigation.
Studies have demonstrated that Chaga extracts may:
- Inhibit tumor growth: Laboratory studies have shown that certain Chaga compounds can slow the growth of various cancer cell lines [18].
- Promote cancer cell death: Some research suggests that Chaga compounds may trigger apoptosis (programmed cell death) in cancer cells while leaving healthy cells unharmed [19].
- Enhance chemotherapy effectiveness: Preliminary studies indicate that Chaga may help improve the effectiveness of conventional cancer treatments while reducing their side effects [20].
Blood Sugar Regulation and Metabolic Support
Traditional use of Chaga for diabetes management has found support in modern research. Several studies have investigated Chaga's potential to help regulate blood sugar levels and support metabolic health.
A 2017 study in mice found that Chaga supplementation helped improve insulin sensitivity and reduce blood glucose levels [21]. The researchers attributed these effects to Chaga's ability to enhance glucose uptake by cells and improve insulin signaling pathways.
Liver Protection and Detoxification
The liver is your body's primary detoxification organ, and Chaga has shown remarkable hepatoprotective (liver-protecting) properties in research studies. This aligns with its traditional use for liver diseases and detoxification support.
Studies have demonstrated that Chaga extracts can:
- Protect against liver damage: Research shows that Chaga can help protect liver cells from damage caused by toxins and oxidative stress [22].
- Support liver regeneration: Some studies suggest that Chaga may help promote the regeneration of healthy liver tissue [23].
- Enhance detoxification processes: Chaga appears to support the liver's natural detoxification pathways, helping the body eliminate harmful substances more effectively [24].
Cardiovascular Health Support
Heart disease remains one of the leading causes of death worldwide, and Chaga's cardiovascular benefits offer another compelling reason to consider this functional mushroom. Research has shown that Chaga may support heart health through multiple mechanisms:
- Cholesterol management: Studies indicate that Chaga may help reduce LDL ("bad") cholesterol while supporting healthy HDL levels [25].
- Blood pressure support: Some research suggests that Chaga compounds may help support healthy blood pressure levels [26].
- Arterial health: The anti-inflammatory and antioxidant properties of Chaga may help protect blood vessels from damage and maintain arterial flexibility [27].
Cognitive Function and Neuroprotection
Emerging research suggests that Chaga may offer neuroprotective benefits, potentially supporting cognitive function and brain health as we age. While this area of research is still developing, early studies are promising.
The antioxidant and anti-inflammatory properties of Chaga may help protect brain cells from damage associated with aging and neurodegenerative diseases. Some researchers are investigating whether Chaga's compounds could help support memory, focus, and overall cognitive performance [28].
How to Incorporate Chaga into Your Wellness Routine
Ready to experience the benefits of Chaga for yourself? Understanding how to choose, prepare, and use Chaga properly is essential for getting the most out of this powerful functional mushroom. Here's your practical guide to making Chaga a part of your daily wellness routine.
Forms of Chaga: Finding What Works for You
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Chaga Powder
One of the most versatile and popular forms. High-quality Chaga powder is made from ground, dried Chaga chunks and can be easily mixed into coffee, tea, smoothies, or other beverages. This is the form we use in our Vital Pour mushroom coffee blends, as it provides excellent bioavailability and mixes seamlessly. -
Chaga Extract
Concentrated extracts offer higher potency and are often standardized for specific bioactive compounds. Available as powders or liquids, they require smaller serving sizes and are a great option for targeted support. -
Chaga Capsules
For convenience and precise dosing, capsules provide a no-fuss way to incorporate Chaga into your daily routine. Look for capsules made from organic, dual-extracted Chaga for maximum potency. -
Chaga Gummies
A tasty and convenient option, gummies make it easy to get your daily dose of Chaga on the go. At Vital Pour, our Mushroom Extract Complex Gummies combine Chaga with other functional mushrooms to support focus, vitality, and immunity—without the need to brew or measure. -
Chaga Chunks
Raw Chaga chunks are traditionally simmered to make Chaga tea. While this method requires more time, it allows you to control the strength and extraction process. -
Chaga Tinctures
Liquid extracts that can be taken directly or added to beverages. Tinctures offer rapid absorption and are especially convenient for travel.
Dosage Guidelines and Recommendations
When it comes to Chaga dosage, there's no universal "one-size-fits-all" recommendation, as optimal amounts can vary based on individual factors, the form of Chaga you're using, and your specific health goals. However, research and traditional use provide helpful guidelines:
General Recommendations:
- Chaga powder: 1-3 grams (1/2 to 1 teaspoon) daily
- Chaga extract: 500-1000 mg daily (follow manufacturer's instructions)
- Chaga tea: 1-2 cups daily made from 1-2 chunks
Starting Protocol: If you're new to Chaga, start with a smaller dose (about half the recommended amount) and gradually increase over 1-2 weeks. This allows your body to adjust and helps you identify your optimal dose.
Timing: Chaga can be taken at any time of day, but many people prefer morning consumption as part of their coffee or tea ritual. Unlike caffeine, Chaga won't interfere with sleep when taken later in the day.
Quality Matters: What to Look for in Chaga Products
Not all Chaga products are created equal. Here's what to look for when choosing a high-quality Chaga supplement:
Source and Harvesting: Look for Chaga that's wild-harvested from pristine northern forests, particularly from birch trees in regions like Siberia, Canada, or Alaska. Avoid products that don't specify their source.
Extraction Method: Dual extraction (both water and alcohol extraction) is considered the gold standard, as it captures both water-soluble and alcohol-soluble compounds.
Third-Party Testing: Choose products that have been tested for purity, potency, and contaminants by independent laboratories.
Organic Certification: While not all wild-harvested Chaga can be certified organic, look for products that meet organic standards when possible.
Standardization: Some products are standardized for specific compounds like polysaccharides or triterpenes, which can help ensure consistent potency.
Safety Considerations and Potential Interactions
Chaga is generally considered safe for most people when used appropriately, but there are some important considerations to keep in mind:
Blood Sugar Effects: Chaga may lower blood sugar levels, so people with diabetes should monitor their blood glucose closely and consult with their healthcare provider before use.
Blood Clotting: Some compounds in Chaga may affect blood clotting. If you're taking anticoagulant medications or have a bleeding disorder, consult your doctor before using Chaga.
Autoimmune Conditions: While Chaga's immune-modulating effects are generally beneficial, people with autoimmune conditions should use caution and consult with a healthcare provider.
Kidney Stones: Chaga contains oxalates, which could potentially contribute to kidney stone formation in susceptible individuals.
Pregnancy and Breastfeeding: There's insufficient research on Chaga's safety during pregnancy and breastfeeding, so it's best to avoid use during these times.
Maximizing Chaga's Benefits
To get the most out of your Chaga supplementation:
Consistency is Key: Like many functional foods, Chaga's benefits tend to build over time with consistent use rather than providing immediate effects.
Combine with Healthy Lifestyle: Chaga works best as part of a comprehensive approach to health that includes a balanced diet, regular exercise, adequate sleep, and stress management.
Consider Cycling: Some practitioners recommend taking periodic breaks from Chaga (such as one week off every month) to prevent tolerance, though this isn't strictly necessary.
Stay Hydrated: Chaga has mild diuretic effects, so ensure you're drinking adequate water throughout the day.
At Vital Pour, we've found that incorporating Chaga into a morning mushroom coffee blend provides an excellent way to start the day with sustained energy and antioxidant support. The earthy, slightly bitter flavor of Chaga complements coffee beautifully while adding a depth of wellness benefits that regular coffee simply can't match.
The Bottom Line: Is Chaga Right for Your Wellness Journey?
After diving deep into the science, history, and practical applications of Chaga mushroom, one thing becomes clear: this remarkable fungus offers far more than just impressive antioxidant claims. While the exact ORAC values may be debated, the substantial body of research supporting Chaga's diverse health benefits speaks for itself.
Chaga represents a perfect example of how traditional wisdom and modern science can converge to offer genuine wellness solutions. For centuries, indigenous peoples recognized its power to support vitality and resilience. Today, scientific research is validating many of these traditional uses while uncovering new potential applications.
What sets Chaga apart from many other supplements is its multifaceted approach to health. Rather than targeting just one aspect of wellness, Chaga works through multiple pathways—supporting immune function, reducing inflammation, protecting against oxidative stress, and potentially offering benefits for cardiovascular health, blood sugar regulation, and cognitive function.
From my personal experience and the feedback we've received from Vital Pour customers, Chaga's benefits tend to be subtle but profound. It's not about dramatic, immediate changes, but rather about building a foundation of resilience and vitality that supports your body's natural ability to maintain health and recover from stress.
Making the Decision
Chaga may be particularly beneficial if you're:
- Looking for natural antioxidant support
- Seeking to support immune system balance
- Interested in traditional remedies backed by modern science
- Wanting to add functional benefits to your daily coffee or tea routine
- Focused on long-term wellness and healthy aging
However, remember that Chaga isn't a magic bullet. Like all functional foods, it works best as part of a comprehensive approach to health that includes a balanced diet, regular exercise, adequate sleep, and stress management.
The Future of Chaga Research
As interest in functional mushrooms continues to grow, we can expect to see more rigorous research into Chaga's mechanisms of action and potential therapeutic applications. Areas of particular interest include its neuroprotective properties, potential role in cancer prevention, and applications in metabolic health.
At Vital Pour, we're committed to staying at the forefront of this research while continuing to provide you with high-quality, science-backed products that harness the power of functional mushrooms like Chaga.
Whether you choose to explore Chaga through our carefully crafted mushroom coffee blends or through other high-quality supplements, you're taking a step toward embracing one of nature's most remarkable wellness allies.
The journey toward optimal health is deeply personal, and Chaga offers a time-tested, scientifically-supported tool to help you along the way. As with any supplement, we recommend consulting with your healthcare provider, especially if you have existing health conditions or take medications.
Welcome to the world of functional mushrooms—where ancient wisdom meets modern wellness, and where nature's pharmacy offers some of its most powerful healing compounds.
References
1.Ern, P. T. Y., Quan, T. Y., Yee, F. S., & Yin, A. C. Y. (2023). Therapeutic properties of Inonotus obliquus (Chaga mushroom): A review. Mycology, 15(2), 144-161. https://pmc.ncbi.nlm.nih.gov/articles/PMC11132974/
2.Thomas, P., Sekhar, A. C., Upreti, R., Mujawar, M. M., & Pasha, S. S. (2020). Optimization of single and combined utilization of betulin and betulinic acid from birch bark to synthesize nanoparticles. Industrial Crops and Products, 155, 112758.
3.Saar, M. (1991). Fungi in Khanty folk medicine. Journal of Ethnopharmacology, 31(2), 175-179.
4.Cao, G., Alessio, H. M., & Cutler, R. G. (1993). Oxygen-radical absorbance capacity assay for antioxidants. Free Radical Biology and Medicine, 14(3), 303-311.
5.USDA. (2012). Oxygen Radical Absorbance Capacity (ORAC) of Selected Foods, Release 2. United States Department of Agriculture. [Database withdrawn]
6.FreshCap Mushrooms. (2025). Does the ORAC Value of Chaga Mushroom Matter? Retrieved from https://freshcap.com/blogs/growing/does-the-orac-value-of-chaga-mushroom-matter
7.Cui, Y., Kim, D. S., & Park, K. C. (2005). Antioxidant effect of Inonotus obliquus. Journal of Ethnopharmacology, 96(1-2), 79-85.
8.Zheng, W., Miao, K., Liu, Y., Zhao, Y., Zhang, M., Pan, S., & Dai, Y. (2010). Chemical diversity of biologically active metabolites in the sclerotia of Inonotus obliquus and submerged culture strategies for up-regulating their production. Applied Microbiology and Biotechnology, 87(4), 1237-1254.
9.Babitskaya, V. G., Shcherba, V. V., Ikonnikova, N. V., Bisko, N. A., & Mitropolskaya, N. Y. (2002). Melanin complex from medicinal tinder fungus, Inonotus obliquus (Pers.: Fr.) Pilát (Chaga) (Aphyllophoromycetideae). International Journal of Medicinal Mushrooms, 4(2), 139-145.
10.Fan, L., Ding, S., Ai, L., & Deng, K. (2012). Antitumor and immunomodulatory activity of water-soluble polysaccharide from Inonotus obliquus. Carbohydrate Polymers, 90(2), 870-874.
11.Kahlos, K., Kangas, L., & Hiltunen, R. (1987). Antitumor activity of some compounds and fractions from an n-hexane extract of Inonotus obliquus (Polyporus obliquus) in vitro. Acta Pharmaceutica Fennica, 96(1), 33-40.
12.Geng, Y., Lu, Z. M., Huang, W., Xu, H. Y., Shi, J. S., & Xu, Z. H. (2013). Bioactivity of fresh and processed Inonotus obliquus. Journal of Natural Medicines, 67(4), 758-765.
13.Glamočlija, J., Ćirić, A., Nikolić, M., Fernandes, Â., Barros, L., Calhelha, R. C., ... & Soković, M. (2015). Chemical characterization and biological activity of Chaga (Inonotus obliquus), a medicinal mushroom. Journal of Ethnopharmacology, 162, 323-332.
14.Ko, S. K., Jin, M., & Pyo, M. Y. (2011). Inonotus obliquus extracts suppress antigen-specific IgE production through the modulation of Th1/Th2 cytokines in ovalbumin-sensitized mice. Journal of Ethnopharmacology, 137(3), 1077-1082.
15.Youn, M. J., Kim, J. K., Park, S. Y., Kim, Y., Kim, S. J., Lee, J. S., ... & Park, H. J. (2008). Chaga mushroom (Inonotus obliquus) induces G0/G1 arrest and apoptosis in human hepatoma HepG2 cells. World Journal of Gastroenterology, 14(4), 511-517.
16.Park, Y. K., Lee, H. B., Jeon, E. J., Jung, H. S., & Kang, M. H. (2004). Chaga mushroom extract inhibits oxidative DNA damage in human lymphocytes as assessed by comet assay. BioFactors, 21(1‐4), 109-112.
17.Ma, L., Chen, H., Dong, P., & Lu, X. (2013). Anti-inflammatory and anticancer activities of extracts and compounds from the mushroom Inonotus obliquus. Food Chemistry, 139(1-4), 503-508.
18.Nakata, T., Yamada, T., Taji, S., Ohishi, H., Wada, S. I., Tokuda, H., ... & Nishino, H. (2007). Structure determination of inonotsuoxides A and B and in vivo anti-tumor promoting activity of inotodiol from the sclerotia of Inonotus obliquus. Bioorganic & Medicinal Chemistry, 15(1), 257-264.
19.Chung, M. J., Chung, C. K., Jeong, Y., & Ham, S. S. (2010). Anticancer activity of subfractions containing pure compounds of Chaga mushroom (Inonotus obliquus) extract in human cancer cells and in Balbc/c mice bearing Sarcoma-180 cells. Nutrition Research and Practice, 4(3), 177-182.
20.Song, Y., Hui, J., Kou, W., Xin, R., Jia, F., Wang, N., ... & Ren, Z. (2008). Identification of Inonotus obliquus and analysis of antioxidation and antitumor activities of polysaccharides. Current Microbiology, 57(5), 454-462.
21.Diao, B. Z., Jin, W. R., & Yu, D. J. (2014). Protective effect of Inonotus obliquus polysaccharide on streptozotocin-induced diabetic mice. International Journal of Biological Macromolecules, 64, 511-515.
22.Hu, Y., Sheng, Y., Yu, M., Li, K., Ren, G., Xu, X., & Liu, Y. (2016). Antioxidant activity of Inonotus obliquus polysaccharide and its amelioration for chronic pancreatitis in mice. International Journal of Biological Macromolecules, 87, 348-356.
23.Hwang, B. S., Lee, I. K., & Yun, B. S. (2016). Phenolic compounds from the fungus Inonotus obliquus and their antioxidant properties. Journal of Antibiotics, 69(2), 108-110.
24.Mishra, S. K., Kang, J. H., Kim, D. K., Oh, S. H., & Kim, M. K. (2012). Orally administered aqueous extract of Inonotus obliquus ameliorates acute inflammation in dextran sulfate sodium (DSS)-induced colitis in mice. Journal of Ethnopharmacology, 143(2), 524-532.
25.Lu, Y., Jia, Y., Xue, Z., Li, N., Liu, J., & Chen, H. (2021). Recent developments in Inonotus obliquus (Chaga mushroom) polysaccharides: Isolation, structural characteristics, biological activities and application. Polymers, 13(9), 1441.
26.Najafzadeh, M., Reynolds, P. D., Baumgartner, A., Jerwood, D., & Anderson, D. (2007). Chaga mushroom extract inhibits oxidative DNA damage in lymphocytes of patients with inflammatory bowel disease. BioFactors, 31(3‐4), 191-200.
27.Shibnev, V. A., Mishin, D. V., Garaev, T. M., Finogenova, N. P., Botikov, A. G., & Deryabin, P. G. (2011). Antiviral activity of Inonotus obliquus fungus extract towards infection caused by hepatitis C virus in cell cultures. Bulletin of Experimental Biology and Medicine, 151(5), 612-614.
28.Reid, T., Kashangura, C., Bakaic, M., Fisher, B., Ghosh, S., Weljie, A., & Adamic, M. (2016). Down-regulation of telomerase activity in Chaga mushroom extract-treated cancer cells. Nutrition and Cancer, 68(7), 1252-1262.
For additional information on functional mushrooms and their health benefits, we recommend exploring resources from the National Center for Biotechnology Information (NCBI) and Examine.com
